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What are the most common symptoms of menopause? And which can hormone therapy treat?

<p><em><a href="https://theconversation.com/profiles/susan-davis-10376">Susan Davis</a>, <a href="https://theconversation.com/institutions/monash-university-1065">Monash University</a></em></p> <p>Despite decades of research, navigating menopause seems to have become harder – with conflicting information on the internet, in the media, and from health care providers and researchers.</p> <p>Adding to the uncertainty, a recent <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00462-8/fulltext">series in the Lancet</a> medical journal challenged some beliefs about the symptoms of menopause and which ones menopausal hormone therapy (also known as hormone replacement therapy) can realistically alleviate.</p> <p>So what symptoms reliably indicate the start of perimenopause or menopause? And which symptoms can menopause hormone therapy help with? Here’s what the evidence says.</p> <h2>Remind me, what exactly is menopause?</h2> <p>Menopause, simply put, is complete loss of female fertility.</p> <p>Menopause is traditionally defined as the final menstrual period of a woman (or person female at birth) who previously menstruated. Menopause is diagnosed after 12 months of no further bleeding (unless you’ve had your ovaries removed, which is surgically induced menopause).</p> <p>Perimenopause starts when menstrual cycles first vary in length by seven or more days, and ends when there has been no bleeding for 12 months.</p> <p>Both perimenopause and menopause are hard to identify if a person has had a hysterectomy but their ovaries remain, or if natural menstruation is suppressed by a treatment (such as hormonal contraception) or a health condition (such as an eating disorder).</p> <h2>What are the most common symptoms of menopause?</h2> <p><a href="https://srh.bmj.com/content/early/2024/02/21/bmjsrh-2023-202099.long">Our study</a> of the highest quality menopause-care guidelines found the internationally recognised symptoms of the perimenopause and menopause are:</p> <ul> <li>hot flushes and night sweats (known as vasomotor symptoms)</li> <li>disturbed sleep</li> <li>musculoskeletal pain</li> <li>decreased sexual function or desire</li> <li>vaginal dryness and irritation</li> <li>mood disturbance (low mood, mood changes or depressive symptoms) but not clinical depression.</li> </ul> <p>However, none of these symptoms are menopause-specific, meaning they could have other causes.</p> <p>In <a href="https://journals.lww.com/menopausejournal/abstract/2015/07000/moderate_to_severe_vasomotor_and_sexual_symptoms.6.aspx">our study of Australian women</a>, 38% of pre-menopausal women, 67% of perimenopausal women and 74% of post-menopausal women aged under 55 experienced hot flushes and/or night sweats.</p> <p>But the severity of these symptoms <a href="https://journals.lww.com/menopausejournal/abstract/2015/07000/moderate_to_severe_vasomotor_and_sexual_symptoms.6.aspx">varies greatly</a>. Only 2.8% of pre-menopausal women reported moderate to severely bothersome hot flushes and night sweats symptoms, compared with 17.1% of perimenopausal women and 28.5% of post-menopausal women aged under 55.</p> <p>So bothersome hot flushes and night sweats appear a reliable indicator of perimenopause and menopause – but they’re not the only symptoms. Nor are hot flushes and night sweats a western society phenomenon, as has been suggested. Women in Asian countries are <a href="https://journals.lww.com/menopausejournal/fulltext/2022/05000/prevalence,_severity,_and_associated_factors_in.9.aspx">similarly affected</a>.</p> <p>Depressive symptoms and anxiety are also often linked to menopause but they’re less menopause-specific than hot flushes and night sweats, as they’re common across the entire adult life span.</p> <p>The <a href="https://srh.bmj.com/content/early/2024/02/21/bmjsrh-2023-202099.long">most robust guidelines</a> do not stipulate women must have hot flushes or night sweats to be considered as having perimenopausal or post-menopausal symptoms. They acknowledge that new mood disturbances may be a primary manifestation of <a href="https://www.cell.com/cell/abstract/S0092-8674(23)00905-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867423009054%3Fshowall%3Dtrue">menopausal hormonal changes</a>.</p> <p>The extent to which menopausal hormone changes impact memory, concentration and problem solving (frequently talked about as “brain fog”) is uncertain. <a href="https://www.tandfonline.com/doi/full/10.1080/13697137.2022.2122792">Some studies</a> suggest perimenopause may impair verbal memory and resolve as women transition through menopause. But strategic thinking and planning (executive brain function) <a href="https://www.tandfonline.com/doi/full/10.1080/13697137.2022.2122792">have not been shown to change</a>.</p> <h2>Who might benefit from hormone therapy?</h2> <p>The Lancet papers <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00462-8/fulltext">suggest</a> menopause hormone therapy <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02799-X/fulltext">alleviates</a> hot flushes and night sweats, but the likelihood of it improving sleep, mood or “brain fog” is limited to those bothered by vasomotor symptoms (hot flushes and night sweats).</p> <p>In contrast, the highest quality <a href="https://srh.bmj.com/content/early/2024/02/21/bmjsrh-2023-202099.long">clinical guidelines</a> consistently identify both vasomotor symptoms and mood disturbances associated with menopause as reasons for menopause hormone therapy. In other words, you don’t need to have hot flushes or night sweats to be prescribed menopause hormone therapy.</p> <p>Often, menopause hormone therapy is prescribed alongside a topical vaginal oestrogen to treat vaginal symptoms (dryness, irritation or urinary frequency).</p> <p>However, none of these guidelines recommend menopause hormone therapy for cognitive symptoms often talked about as “brain fog”.</p> <p>Despite musculoskeletal pain being the most common menopausal symptom in <a href="https://journals.lww.com/menopausejournal/abstract/2016/07000/prevalence_and_severity_of_vasomotor_symptoms_and.6.aspx">some populations</a>, the effectiveness of menopause hormone therapy for this specific symptoms still needs to be studied.</p> <p>Some guidelines, such as an <a href="https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783">Australian endorsed guideline</a>, support menopause hormone therapy for the prevention of osteoporosis and fracture, but not for the prevention of any other disease.</p> <h2>What are the risks?</h2> <p>The greatest concerns about menopause hormone therapy have been about breast cancer and an increased risk of a deep vein clot which might cause a lung clot.</p> <p>Oestrogen-only menopause hormone therapy is <a href="https://www.nice.org.uk/guidance/ng23">consistently considered</a> to cause little or no change in breast cancer risk.</p> <p>Oestrogen taken with a progestogen, which is required for women who have not had a hysterectomy, <a href="https://www.moh.gov.my/moh/resources/Penerbitan/CPG/Women%20Health/CPG_Management_of_Menopause_2022_e-version-1.pdf">has been associated with a small increase</a> in the risk of breast cancer, although any <a href="https://www.bmj.com/content/bmj/371/bmj.m3873.full.pdf">risk appears to vary</a> according to the type of therapy used, the dose and duration of use.</p> <p>Oestrogen taken orally has also been associated with an increased risk of a deep vein clot, although the risk varies according to the formulation used. This risk is avoided by using estrogen patches or gels <a href="https://www.bmj.com/content/bmj/364/bmj.k4810.full.pdf">prescribed at standard doses</a></p> <h2>What if I don’t want hormone therapy?</h2> <p>If you can’t or don’t want to take menopause hormone therapy, there are also effective non-hormonal prescription therapies available for troublesome hot flushes and night sweats.</p> <p>In Australia, most of these options are “off-label”, although the new medication <a href="https://australianprescriber.tg.org.au/articles/management-of-menopause.html">fezolinetant</a> has just been <a href="https://www.tga.gov.au/resources/artg/401401">approved</a> in Australia for postmenopausal hot flushes and night sweats, and is expected to be available by mid-year. Fezolinetant, taken as a tablet, acts in the brain to stop the chemical neurokinin 3 triggering an inappropriate body heat response (flush and/or sweat).</p> <p>Unfortunately, most over-the-counter treatments promoted for menopause are either <a href="https://srh.bmj.com/content/early/2024/02/21/bmjsrh-2023-202099.long">ineffective or unproven</a>. However, cognitive behaviour therapy and hypnosis <a href="https://journals.lww.com/menopausejournal/abstract/2023/06000/the_2023_nonhormone_therapy_position_statement_of.4.aspx">may provide symptom relief</a>.</p> <p><em>The Australasian Menopause Society has useful <a href="https://www.menopause.org.au/health-info/fact-sheets">menopause fact sheets</a> and a <a href="https://www.menopause.org.au/health-info/find-an-ams-doctor">find-a-doctor</a> page. The <a href="https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783">Practitioner Toolkit for Managing Menopause</a> is also freely available.</em><!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/225174/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em><a href="https://theconversation.com/profiles/susan-davis-10376">Susan Davis</a>, Chair of Women's Health, <a href="https://theconversation.com/institutions/monash-university-1065">Monash University</a></em></p> <p><em>Image credits: Getty Images </em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/what-are-the-most-common-symptoms-of-menopause-and-which-can-hormone-therapy-treat-225174">original article</a>.</em></p>

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Why do I keep getting urinary tract infections? And why are chronic UTIs so hard to treat?

<p><em><a href="https://theconversation.com/profiles/iris-lim-1204657">Iris Lim</a>, <a href="https://theconversation.com/institutions/bond-university-863">Bond University</a></em></p> <p>Dealing with chronic urinary tract infections (UTIs) means facing more than the occasional discomfort. It’s like being on a never ending battlefield against an unseen adversary, making simple daily activities a trial.</p> <p>UTIs happen when bacteria sneak into the urinary system, causing pain and frequent trips to the bathroom.</p> <p>Chronic UTIs take this to the next level, coming back repeatedly or never fully going away despite treatment. <a href="https://www.ncbi.nlm.nih.gov/books/NBK557479/">Chronic UTIs</a> are typically diagnosed when a person experiences two or more infections within six months or three or more within a year.</p> <p>They can happen to anyone, but some are more prone due to their <a href="https://www.urologyhealth.org/urology-a-z/u/urinary-tract-infections-in-adults">body’s makeup or habits</a>. Women are more likely to get UTIs than men, due to their shorter urethra and hormonal changes during menopause that can decrease the protective lining of the urinary tract. Sexually active people are also at greater risk, as bacteria can be transferred around the area.</p> <p>Up to <a href="https://www.urologyhealth.org/urology-a-z/u/urinary-tract-infections-in-adults#Related%20Resources">60% of women</a> will have at least one UTI in their lifetime. While effective treatments exist, <a href="https://www.health.harvard.edu/bladder-and-bowel/when-urinary-tract-infections-keep-coming-back#:%7E:text=Your%20urine%20might%20be%20cloudy,they%20take%20on%20your%20life.">about 25%</a> of women face recurrent infections within six months. Around <a href="https://sciendo.com/article/10.33073/pjm-2019-048?tab=article">20–30%</a> of UTIs don’t respond to standard antibiotic. The challenge of chronic UTIs lies in bacteria’s ability to shield themselves against treatments.</p> <h2>Why are chronic UTIs so hard to treat?</h2> <p>Once thought of as straightforward infections cured by antibiotics, we now know chronic UTIs are complex. The cunning nature of the bacteria responsible for the condition allows them to hide in bladder walls, out of antibiotics’ reach.</p> <p>The bacteria form biofilms, a kind of protective barrier that makes them nearly impervious to standard antibiotic treatments.</p> <p>This ability to evade treatment has led to a troubling <a href="https://theconversation.com/rising-antibiotic-resistance-in-utis-could-cost-australia-1-6-billion-a-year-by-2030-heres-how-to-curb-it-149543">increase in antibiotic resistance</a>, a global health concern that renders some of the conventional treatments ineffective.</p> <p>Antibiotics need to be advanced to keep up with evolving bacteria, in a similar way to the flu vaccine, which is updated annually to combat the latest strains of the flu virus. If we used the same flu vaccine year after year, its effectiveness would wane, just as overused antibiotics lose their power against bacteria that have adapted.</p> <p>But fighting bacteria that resist antibiotics is much tougher than updating the flu vaccine. Bacteria change in ways that are harder to predict, making it more challenging to create new, effective antibiotics. It’s like a never-ending game where the bacteria are always one step ahead.</p> <p>Treating chronic UTIs still relies heavily on antibiotics, but doctors are getting crafty, changing up medications or prescribing low doses over a longer time to outwit the bacteria.</p> <p>Doctors are also placing a greater emphasis on thorough diagnostics to accurately identify chronic UTIs from the outset. By asking detailed questions about the duration and frequency of symptoms, health-care providers can better distinguish between isolated UTI episodes and chronic conditions.</p> <p>The approach to initial treatment can significantly influence the likelihood of a UTI becoming chronic. Early, targeted therapy, based on the specific bacteria causing the infection and its antibiotic sensitivity, may reduce the risk of recurrence.</p> <p>For post-menopausal women, <a href="https://link.springer.com/article/10.1007/s00192-020-04397-z">estrogen therapy</a> has shown promise in reducing the risk of recurrent UTIs. After menopause, the decrease in estrogen levels can lead to changes in the urinary tract that makes it more susceptible to infections. This treatment restores the balance of the vaginal and urinary tract environments, making it less likely for UTIs to occur.</p> <p>Lifestyle changes, such as <a href="https://journals.lww.com/co-nephrolhypertens/FullText/2013/05001/Impact_of_fluid_intake_in_the_prevention_of.1.aspx">drinking more water</a> and practising good hygiene like washing hands with soap after going to the toilet and the recommended front-to-back wiping for women, also play a big role.</p> <p>Some swear by cranberry juice or supplements, though researchers are still figuring out <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001322.pub2/full">how effective these remedies truly are</a>.</p> <h2>What treatments might we see in the future?</h2> <p>Scientists are currently working on new treatments for chronic UTIs. One promising avenue is the development of <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052183/pdf/pathogens-12-00359.pdf">vaccines</a> aimed at preventing UTIs altogether, much like flu shots prepare our immune system to fend off the flu.</p> <p>Another new method being looked at is called <a href="https://link.springer.com/article/10.1007/s12223-019-00750-y">phage therapy</a>. It uses special viruses called bacteriophages that go after and kill only the bad bacteria causing UTIs, while leaving the good bacteria in our body alone. This way, it doesn’t make the bacteria resistant to treatment, which is a big plus.</p> <p>Researchers are also exploring the potential of <a href="https://www.mdpi.com/2079-6382/12/1/167">probiotics</a>. Probiotics introduce beneficial bacteria into the urinary tract to out-compete harmful pathogens. These good bacteria work by occupying space and resources in the urinary tract, making it harder for harmful pathogens to establish themselves.</p> <p>Probiotics can also produce substances that inhibit the growth of harmful bacteria and enhance the body’s immune response.</p> <p>Chronic UTIs represent a stubborn challenge, but with a mix of current treatments and promising research, we’re getting closer to a day when chronic UTIs are a thing of the past.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/223008/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/iris-lim-1204657">I<em>ris Lim</em></a><em>, Assistant Professor, <a href="https://theconversation.com/institutions/bond-university-863">Bond University</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/why-do-i-keep-getting-urinary-tract-infections-and-why-are-chronic-utis-so-hard-to-treat-223008">original article</a>.</em></p>

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Grant Denyer serenades one of Australia's oldest Deal or No Deal contestants

<p>In the latest feelgood episode of <em>Deal or No Deal</em>, 94-year-old contestant  Phyllis Goldsack was given the chance to win $100,000. </p> <p>As one of the oldest contestants on the show, Phyllis kept everyone entertained as she challenged the banker.</p> <p>In one particularly sweet moment, game show host Grant Denyer serenaded her with a special song.</p> <p>A clip of the moment was shared on X, formerly known as Twitter, with the caption: "We're not crying, you're crying,"  and the crying emoji. </p> <p>"Okay the deal is, if I serenade you, with the song of your choosing, you get $800 from my pocket," Grant told Phyllis in the show. </p> <p>The audience were touched when Phyllis revealed that her late husband only ever sang her one song when he proposed, <em style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;">You Are My Sunshine.</em></p> <blockquote class="twitter-tweet"> <p dir="ltr" lang="en">We're not crying, you're crying! 😭<a href="https://twitter.com/hashtag/DealOrNoDealAU?src=hash&amp;ref_src=twsrc%5Etfw">#DealOrNoDealAU</a> 6.00 Weeknights on <a href="https://twitter.com/Channel10AU?ref_src=twsrc%5Etfw">@channel10au</a> and 10 Play. <a href="https://t.co/CVR0M5rq7y">pic.twitter.com/CVR0M5rq7y</a></p> <p>— Deal Or No Deal Australia (@DealOrNoDealAUS) <a href="https://twitter.com/DealOrNoDealAUS/status/1756942546767339956?ref_src=twsrc%5Etfw">February 12, 2024</a></p></blockquote> <p><span style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;">"Should we do it one more time maybe?" Grant asked Phyllis who eagerly replied: "yes, you sing it for me". </span></p> <p><span style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;">The crowd joined in and serenaded the 94 year old. </span></p> <p>“Thank you, you know you have made me feel so happy,” she told Grant. </p> <p>Although Phyllis did not win the $100,000, she went home $9,255 richer, which was the best offer she received from the banker. </p> <p>“That’s why I do this show!” Grant said. </p> <p><em>Images: X</em></p>

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Are catnip and treats like it safe for cats? Here’s how they affect their minds and moods

<p><em><a href="https://theconversation.com/profiles/mia-cobb-15211">Mia Cobb</a>, <a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a> and <a href="https://theconversation.com/profiles/anne-quain-12802">Anne Quain</a>, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a></em></p> <p>Cats kept indoors can <a href="https://safeandhappycats.com.au/">live a good life</a> when they get access to a variety of positive experiences. Examples include performing natural behaviours, feeling safe at home and using their full sensory capabilities, including their sense of smell.</p> <p>Plants such as catnip, cat thyme and silver vine are potent smelly stimulants that can affect cat minds and moods.</p> <p>Ever wondered if these mind-altering substances are safe gifts for our feline friends? And importantly, is it OK to provide these, or is offering catnip to a cat like offering alcohol to a child?</p> <h2>Catnip, cat thyme and silver vine, oh my!</h2> <p>Owners who are concerned about their cats feeling bored and frustrated might offer them fresh or dried catnip (<em>Nepeta cataria</em>), silver vine (<em>Actinidia polygama</em>), cat thyme (<em>Teucrium marum</em>) or other plant materials such as valerian (<em>Valeriana officinalis</em>) and Tatarian honeysuckle (<em>Lonicera tatarica</em>). These last couple <a href="https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-017-0987-6">could offer an alternative</a> if your cat doesn’t respond to catnip.</p> <p>Toys filled with the leaves or extracts of these plants can cause apparently euphoric behaviour in domestic cats (as well as big cats like leopards and jaguars). Not all cats respond this way to these smells, which is <a href="https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-022-01369-1">believed to have a genetic basis</a>.</p> <h2>Are these treats safe for cats?</h2> <p>Cats have a highly developed sense of smell. Some plants release chemical compounds to deter insects or to attract predators of insects that might otherwise destroy them. This includes <a href="https://www.science.org/doi/10.1126/sciadv.aba0721">nepetalactone</a>, an ingredient isolated from catnip and silver vine.</p> <p>Indeed, <a href="https://www.science.org/content/article/why-cats-are-crazy-catnip">it has been argued </a> that exposure to nepetalactone leads to an increase in feel-good hormones in cats. It may also act as a <a href="https://www.science.org/doi/10.1126/sciadv.abd9135">natural mosquito repellent</a> (note that it does not repel all mosquitoes and is not effective for flea or tick control).</p> <p>This may be why sniffing catnip, silver vine and some other plants causes cats to roll on their backs and rub their chins, cheeks and bodies on the plants. Other <a href="https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-017-0987-6">observed behaviours</a> include: licking, shaking their head while carrying plant material in their mouth, drooling, kicking the plant material with their hind feet, and a “wavelike” motion of the skin over their backs as muscles contract and relax.</p> <p>These responses <a href="https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-017-0987-6">generally don’t last long</a>, usually seconds to minutes, before cats relax or resume their normal behaviour.</p> <p>Rather than becoming addicted to these substances, cats are more likely to become habituated and desensitised, with the plants having less effect over time. When sniffed, these plants <a href="https://www.cell.com/iscience/fulltext/S2589-0042(23)01925-9">appear</a> to have <a href="https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-022-01369-1">no adverse effects</a> on cats.</p> <figure><iframe src="https://www.youtube.com/embed/yNUz4zQTA1E?wmode=transparent&amp;start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe><figcaption><span class="caption">Cats (and a dog!) react to the active compound in catnip and silver vine, nepetalactone.</span></figcaption></figure> <h2>Is it ethical to alter the minds of our cats?</h2> <p>When considering how to improve the lives of animals we care for, we tend to focus on whether the benefits outweigh the potential harms.</p> <p>Despite some marketing claims that these plants activates the brain’s opioid system, delivering a “natural high” for cats, there is no evidence these substances actually alter the minds of cats in the same way as alcohol or other drugs alter the minds of humans.</p> <p>The marketing of these cat treats as “kitty crack” or “<a href="https://www.meowijuana.com/">meowijuana</a>” and silver vine sticks as “<a href="https://www.nekopiapets.com.au/product-page/joycat-cat-cigarettes-silvervine-stick">kitty cigarettes</a>” is likely to deter some people from offering their cats <a href="https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-022-01369-1">this kind of olfactory stimulation</a>.</p> <p>Unlike offering alcohol to a child, though, the evidence suggests our cats are OK when given access to these treats. These items won’t induce psychosis and won’t lead to addiction or withdrawal symptoms. And we don’t need to worry about our cats operating heavy machinery or making important decisions under the influence of mind-altering substances!</p> <p>Provided they can walk away at any time, it seems reasonable to let them opt in to a fun time.</p> <p>In fact, we harness the power of cats’ sense of smell in other ways by using <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435919/">synthetic feline facial pheromones</a>. This can help reduce fear, anxiety and distress in cats. These substances can come in useful in settings such as multi-cat households or when moving house.</p> <h2>How to make sure your cat has the purr-fect time</h2> <p>Offering a range of smells (olfactory stimulation) is just one way to ensure your cat has a varied and interesting life. Here are some tips:</p> <ul> <li> <p>offer cats choices to interact with treats and toys – don’t force them</p> </li> <li> <p>rotate the toys and experiences on offer, so every day offers something fresh</p> </li> <li> <p>offer items that cats can scratch – scratching posts and corrugated cardboard are popular items</p> </li> <li> <p>if you are concerned your cat has swallowed part of a toy or seems unwell, check in with your vet.</p> </li> </ul> <p>Given the short-lived effects of these plant-based olfactory stimulants on cats, it is important that we <a href="https://www.sciencedirect.com/science/article/abs/pii/S0168159119301054">optimise their environment, lifestyle and interactions</a> with humans to improve their welfare. We can’t just rely on catnip or silver vine to give our cats a good life indoors – it’s really up to us!<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/214947/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/mia-cobb-15211"><em>Mia Cobb</em></a><em>, Research Fellow, Animal Welfare Science Centre, <a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a> and <a href="https://theconversation.com/profiles/anne-quain-12802">Anne Quain</a>, Senior Lecturer, Sydney School of Veterinary Science, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a></em></p> <p><em>Image credits: Getty Images </em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/are-catnip-and-treats-like-it-safe-for-cats-heres-how-they-affect-their-minds-and-moods-214947">original article</a>.</em></p>

Family & Pets

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Woolworths impresses customers with welcome "treat"

<p>Woolworths have given their customers a reason to smile after giving shoppers an unexpected offer. </p> <p>The supermarket giant has been praised for a simple but thoughtful gesture to customers trying to beat the heat while doing groceries. </p> <p>On a particularly hot day, a Woolworths store put bins of ice and bottles of water by the entrance for shoppers to take, with no charge. </p> <p>"Dear customers, we are in for a warm day. Stay safe and hydrated. Please enjoy a bottle of cold water from the store team," read signs attached to tubs at the shop.</p> <p>The small but significant gesture didn't go unnoticed by grateful shoppers, with one customer sharing a photo of the freebies on Facebook and describing it as a "great idea".</p> <p>Another shopper agreed, commenting, "As it was 40°C in Adelaide today, cold water would have been a treat."</p> <p>"Can grab some apples for the kids and a bottle of water," added someone else, referencing the free fruit for children also offered by the retailer.</p> <p>A spokesperson from Woolworths shared with <a href="https://au.news.yahoo.com/woolworths-stuns-with-unexpected-offer-for-customers-085030601.html" target="_blank" rel="noopener"><em>Yahoo News Australia</em></a> that this offer embodies a commitment to acts of kindness that are encouraged among the retailer's network of supermarkets.</p> <p>"Our store teams try and bring a little good to our customers every day," the spokesperson said.</p> <p>Not everyone was impressed by the generous offer, however, including a critic who suggested that what the supermarket was "really saying is that there's no air conditioning in their store".</p> <p>Others were also quick to comment that while the bottles of water were a nice offer, what would really help them would be a reduction in soaring grocery prices as the cost of living crisis continues. </p> <p><em>Image credits: Facebook / Shutterstock</em></p>

Caring

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Name that rash: 6 common skin conditions (and how to treat them)

<p><strong>Psoriasis</strong></p> <p><span style="text-decoration: underline;"><em>What psoriasis is like:</em></span> Psoriasis is made of red, scaly plaques that can be itchy and painful. It can show up anywhere but is most commonly found on the scalp, as well as the outside of the elbows and knees. It usually starts between age 10 and 30 and tends to be a chronic condition. “It’s a stubborn disease that waxes and wanes, so people have it for their whole lives,” says dermatologist Paul Cohen.</p> <p><span style="text-decoration: underline;"><em>What causes psoriasis:</em></span> This skin rash is the result of your immune system attacking the skin’s cells, and creating new ones too quickly, which then build up into the plaques. There’s no one single cause, but the condition runs in families. Stress, obesity, smoking and having many infections (particularly strep throat) increase your risk.</p> <p><span style="text-decoration: underline;"><em>How to treat psoriasis:</em></span> The first step is generally topical steroids, which can be used for a week or two at a time to clear up the plaques. For ongoing treatment, people use a synthetic form of vitamin D (which slows skin growth), medicated shampoos and retinoids (a topical version of vitamin A). Daily exposure to sunlight also seems to help, as does moisturising well. For more serious cases, options include oral medications that suppress the immune system and phototherapy done in a doctor’s office with a special light. (Discover more applications of light therapy.)</p> <p><span style="text-decoration: underline;"><em>Possible red flag:</em></span> Serious cases can involve the joints, a condition called psoriatic arthritis. Also, psoriasis increases your chances of having some other diseases, including type 2 diabetes, cardiovascular disease and autoimmune conditions such as Crohn’s – all of which are, like psoriasis, linked to inflammation.</p> <p><strong>Hives</strong></p> <p><span style="text-decoration: underline;"><em>What hives are like:</em></span> Hives are itchy, raised welts that often have a red ring around them. Their most salient characteristic is that they disappear after about a day, only to show up later in a different location. They come in two forms: acute, which lasts six weeks or less, and chronic.</p> <p><span style="text-decoration: underline;"><em>What causes hives:</em></span> Hives are often the result of the body releasing histamine as part of an allergic reaction to drugs, food or some other irritant. They also commonly appear after a viral illness, as a side effect of your immune system revving up to battle the disease. “There are a number of potential triggers,” says dermatologist Katie Beleznay. In most cases, she adds, the specific origin is never determined.</p> <p><span style="text-decoration: underline;"><em>How to treat hives:</em></span> Since hives are a histamine reaction, over-the-counter antihistamines are the first line of defence. If that doesn’t clear them up, ask a doctor if you should use a stronger antihistamine or oral prednisone, an anti-inflammatory medication.</p> <p><span style="text-decoration: underline;"><em>Possible red flag:</em></span> Rarely, people suffer from ongoing outbreaks of hives almost daily for six weeks or more, a condition called chronic idiopathic urticaria (CIU). The treatment for CIU is the same as for regular hives, but in some cases, it can also be a sign of an underlying thyroid disease or cancer.</p> <p><strong>Eczema</strong></p> <p><span style="text-decoration: underline;"><em>What eczema is like:</em></span> Eczema presents as patches of red, scaly skin that are extremely itchy, especially at night. These rashes often appear on the inside of your elbows and knees. If it’s more serious, the skin might blister or look thickened and white in those areas.</p> <p><span style="text-decoration: underline;"><em>What causes eczema:</em></span> Eczema is the result of having a weakened skin barrier, which can lead to inflammation and an overreaction from your immune system. Most people are born with it, and your genes are partly to blame. “You’re more predisposed to eczema if you have a family history of asthma, hay fever or the condition itself,” says Lisa Kellett, a dermatologist in Toronto. Some research also suggests that it might be a reaction to pollution, or to not being exposed to enough germs in childhood. (Kids who have dogs, for example, are less likely to have eczema.)</p> <p><span style="text-decoration: underline;"><em>How to treat eczema:</em></span> For general maintenance, apply a thick, hypoallergenic moisturizer to affected areas immediately after a bath or shower and at night. More serious flares will need topical prescription steroid creams or non-steroid immunosuppressant creams. People with stubborn eczema might also try phototherapy, which uses UVB light to help calm your immune system and reduce itchiness.</p> <p><span style="text-decoration: underline;"><em>Possible red flag:</em></span> Rarely, what looks like eczema is actually skin cancer, as both can appear red and scaly. “The difference with skin cancer is that it doesn’t go away if you use a steroid,” says Kellett.</p> <p><strong>Contact Dermatitis</strong></p> <p><span style="text-decoration: underline;"><em>What contact dermatitis is like:</em></span> Contact dermatitis is a variation of eczema, and it looks similar – red, itchy patches on your skin. But unlike that chronic condition, this skin rash is a reaction to something specific and appears only where the offending object has made contact. “Poison ivy, for instance, will show up as a streak where the branch touched the skin,” says Beleznay.</p> <p><span style="text-decoration: underline;"><em>What causes contact dermatitis:</em></span> Besides poison ivy, other common culprits that can cause the immune system to go into overdrive are face cream, jewellery or fragrances. You can also develop a new intolerance to something you’ve used for a long time, such as Polysporin. If it’s not clear what caused it, your dermatologist can do a patch test, putting small amounts of suspected substances on your skin to see if you react.</p> <p><span style="text-decoration: underline;"><em>How to treat contact dermatitis:</em></span> Contact dermatitis is treated with topical steroids, or a stronger oral one, to calm down your immune system and stop the reaction.</p> <p><span style="text-decoration: underline;"><em>Possible red flag:</em></span> Like eczema, the red and scaly presentation of contact dermatitis could be confused for skin cancer, which is another reason to visit your doctor if you’re not sure what caused it.</p> <p><strong>Rosacea</strong></p> <p><span style="text-decoration: underline;"><em>What rosacea is like:</em></span> As rosacea is a dilation of the blood vessels in your cheeks and nose, it often presents as red, sensitive skin in those places. Another form of the condition also includes bumps that resemble acne. For some people, the skin on their nose thickens, making it appear larger.</p> <p><span style="text-decoration: underline;"><em>What causes rosacea:</em></span> We don’t know what brings rosacea on, but, as with eczema, you’re more likely to have it if others in your family do, too. You’re also prone to acquire the condition if you have sun-damaged skin. “Rosacea usually begins around the age of 35 and gets worse with time,” says Kellett. People often find their flare-ups come after eating or drinking specific things.</p> <p><span style="text-decoration: underline;"><em>How to treat rosacea:</em></span> For many, preventing activation of their rosacea is as simple as avoiding triggers – but that’s easier than it sounds and can be a serious test of a sufferer’s willpower. “Those are often the good things in life,” says Beleznay, citing coffee, spicy foods and alcohol as common aggravators. Some women find that everyday makeup is enough to cover up the cosmetic impact of the condition, while others use prescription creams or laser or light therapy to constrict the blood vessels in the cheeks and reduce redness. For those whose rosacea includes bumps, topical creams or oral antibiotics often get rid of them.</p> <p><span style="text-decoration: underline;"><em>Possible red flag:</em></span> Rarely, what looks like rosacea can be confused for the butterfly rash that’s a symptom of lupus, a serious autoimmune disease. The butterfly rash is named as such because of the shape it makes on the nose and both cheeks.</p> <p><strong>Shingles</strong></p> <p><span style="text-decoration: underline;"><em>What shingles is like:</em></span> Shingles normally starts out as a tingly, numb or bruised feeling in a small area, most commonly a patch on the abdomen. A few days later, a painful skin rash with blisters appears over those places. As the condition follows the path of a nerve, the rash eventually presents as a stripe that lasts from two to six weeks.</p> <p><span style="text-decoration: underline;"><em>What causes shingles:</em></span> This one’s easy: chicken pox. Even once you have fully recovered from that virus, your body never totally beats it; it simply retreats and lies dormant in your nerve cells, where, decades later, it can re-erupt as shingles. You’re more likely to get them if you’re immunocompromised or over 50, the age at which most public health agencies recommend you get the vaccine.</p> <p><span style="text-decoration: underline;"><em>How to treat shingles:</em></span> If you suspect you have shingles, see your doctor immediately. “You have to go right away because studies show that people do much better if the antiviral pills are started within 72 hours of the rash onset,” says Cohen. Additionally, sufferers are often given medication, like a local anaesthetic or codeine, to help control the pain.</p> <p><span style="text-decoration: underline;"><em>Possible red flag:</em></span> The real worry with shingles is that for some people, if it is not contained quickly, the virus can lead to longer-term pain lasting over three months and in some cases over a year. If the skin rash appears on the face, it can even cause blindness.</p> <p><em>Image credits: Getty Images</em></p> <p><em>This article originally appeared on <a href="https://www.readersdigest.com.au/healthsmart/name-that-rash-6-common-skin-conditions-and-how-to-treat-them" target="_blank" rel="noopener">Reader's Digest</a>. </em></p>

Body

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5 time-saving laundry tricks

<p>Doing laundry seems to be a never-ending chore. These simple tricks will make your life a little easier next time you do your washing.</p> <p><strong>1. Use lingerie bag for socks</strong></p> <p>Losing and then pairing mismatched socks makes laundry a bigger task than what it already is. Make sock washing easier by washing all your socks together in a lingerie bag. Gone will be the days that you find odd socks stuck in a pair of jeans or hiding in the washing machine.</p> <p><strong>2. Make detergent yourself</strong></p> <p>If you are ever concerned with the chemicals and ingredients in laundry detergent then you can opt for a natural detergent by making it yourself. To make homemade detergent, stir together one bar shaved bar soap, 1 cup of borax and one cup of washing soda. You can put the ingredients in a food processor or blender to create a fine powder. Simply store in a sealed container.</p> <p><strong>3. Make dryer sheets yourself</strong></p> <p>To make budget-friendly dryer sheets, you will need old scraps of cloth, essential oils and white vinegar. Mix one cup of white vinegar with roughly 25 drops of essential oils. Fold the cloth scraps and place them into a jar or storage container. Moisten the cloth with vinegar mixture but do not saturate them. Then use one cloth per dryer load to freshen laundry.</p> <p><strong>4. Use chalk to remove grease stains</strong></p> <p>If you have any chalk handy it can pre-treat grease stains. The chalk powder helps absorb the grease and will leave your clothes looking clean again.</p> <p><strong>5. Use baby shampoo to unshrink clothes</strong></p> <p>If you ever accidentally shrink one of your favourite items of clothes then reach for baby shampoo. Baby shampoo can stretch clothing and restore it to its former shape and size.</p> <p><em>Image credits: Getty Images </em></p>

Home & Garden

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Carrie Bickmore's rumoured TV return

<p>Carrie Bickmore is rumoured to be the next host of the upcoming reboot of the iconic Aussie game show <em>Deal or No Deal. </em></p> <p>The former <em>The Project </em>anchor is the front-runner to host the series which is set to air on Channel 10 next year. </p> <p>It is understood that the network is desperate to get Bickmore onboard, but with fame comes a hefty price tag. </p> <p>“She’s one of the biggest stars in Australia and she comes with a very big price tag,” a source reportedly told <em>New Idea</em>, revealing that her current rate is believed to be over $500,000.</p> <p>“Deal or No Deal is currently lined up to air at 6pm as the lead-in to The Project - with hopes those eyeballs that tune in to the game show will stay on to watch Sarah Harris, Waleed Aly, and the gang,” the source added. </p> <p>“It’d be a win-win for the network, getting Carrie back on TV and hosting a show that could actually get people back into watching The Project - it’s sort of genius.”</p> <p>However, she isn't the only star the broadcaster have their eyes on. </p> <p>Peter Helliar is also rumoured to be part of the line up, with a much cheaper price tag. </p> <p><em>Deal or No Deal</em> first aired in 2003 on Channel 7, and had a ten-year run before the show was axed.</p> <p>Although there's no set date for the when the show will air just yet, they are looking for their next stars with <a href="https://eu.castitreach.com/ag/esgau/dond/welcome.html" target="_blank" rel="noopener">casting calls</a> open for those over 18. </p> <p>Image: </p>

TV

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Pilot praised for revealing simple trick to cope with severe turbulence

<p>A pilot has shared his simple "water bottle trick" for anxious passengers to cope with turbulence in the air. </p> <p>Sydney-sider Jimmy Nicholson and his wife Holly recently shared a video of their bumpy flight with "horrible" turbulence that went viral on TikTok, after Jimmy shared his tips on how to cope with the anxiety. </p> <p>In the video, his wife was filmed hyperventilating, and at one point even pulled out a sick bag. The couple held hands as other passengers were heard screaming during the wild turbulence. </p> <p>“So we’re at the back of the plane so it’s worse here," Jimmy, who looked more calm than most passengers, said in the clip. </p> <p>“It’s not comfortable, probably some of the worst I’ve been in. Could be widespread storms so pilots just have to pick their path of least resistance and go through it so nothing to worry about.</p> <p>“Planes are built to withstand way worse. Not fun evidently, but completely fine.</p> <p>“I’m a pilot and actually fly this aircraft type (Airbus). Here’s why you have nothing to worry about.”</p> <p>For those terrified of turbulence, Jimmy suggested looking at the water inside an upside down water bottle. </p> <p>“Water bottle trick: The water isn’t moving much, is it?” he said.</p> <p> </p> <div class="embed" style="box-sizing: inherit; margin: 0px; padding: 0px; border: 0px; font-size: 16px; vertical-align: baseline; outline: none !important;"><iframe class="embedly-embed" style="box-sizing: inherit; margin: 0px; padding: 0px; border: 0px; font-size: 16px; vertical-align: baseline; outline: none !important; width: 603px; max-width: 100%;" title="tiktok embed" src="https://cdn.embedly.com/widgets/media.html?src=https%3A%2F%2Fwww.tiktok.com%2Fembed%2Fv2%2F7272043055874723073&amp;display_name=tiktok&amp;url=https%3A%2F%2Fwww.tiktok.com%2F%40jimmy_nicholson%2Fvideo%2F7272043055874723073%3F_r%3D1%26_t%3D8fD3XY38vB4&amp;image=https%3A%2F%2Fp16-sign-sg.tiktokcdn.com%2Fobj%2Ftos-alisg-p-0037%2FoM6n8BXn3ENnHuqtQEMUDb4jUe6fkgAi0BORgF%3Fx-expires%3D1693292400%26x-signature%3DrKGHV84h94FBzJrVu4RsUV8upK0%253D&amp;key=5b465a7e134d4f09b4e6901220de11f0&amp;type=text%2Fhtml&amp;schema=tiktok" width="340" height="700" frameborder="0" scrolling="no" allowfullscreen="allowfullscreen"></iframe></div> <p>He added that if the water appears to be moving gently in the water bottle, then the turbulence feels worse than it actually is. </p> <p>“Remind yourself it’s completely normal. The plane isn’t going to fall out of the sky,” he said.</p> <p>The pilot suggested turning on the air conditioning and looking out the window to calm your nerves. </p> <p>The video ended with passengers clapping after they rode out the turbulence, and the TikTok has been viewed over 2.4 million times, with many thanking Jimmy for his tips. </p> <p>“This helps so much! We need more pilots to post about the stuff the rest of us think will be the last minutes of our lives,” one wrote.</p> <p>“Thank you for explaining this. I’m an anxious flyer and seeing you talk about it has helped," commented another. </p> <p>“Thank you for this video. I saved it and going to watch it in my flights when I am frightened," wrote a third. </p> <p><em>Images: TikTok/ Instagram</em></p>

Travel Trouble

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Try these tricks the next time small talk becomes unbearable

<p><strong>Real talk</strong></p> <p>Bonnie Todd runs 250 food tours a year – a job that puts her in contact with hundreds of new people every week. Food-lovers come to her for an introduction to local tastes and flavours. And a large part of what keeps her guests satisfied, and willing to recommend her business to others, is the personal connection she makes with them.</p> <p>“I try to get past the small talk and general recommendations pretty quickly,” says the 42-year-old. “It’s all about finding common ground within the group, and trying to make it a unique experience. So I’m always asking questions. And when I find that spark of commonality, I dig into it.”</p> <p>The practice is key to Todd’s approach because, unlike many tours, hers require people to sit together sharing food and drinks. When groups don’t gel, or never get past the “Where are you from?” stage, what should be a stimulating experience can turn into an awkward and draining couple of hours.</p> <p>We’ve all been there: trapped in a superficial exchange that bounces aimlessly from one meaningless topic to the next. It can make you never want to step foot into another party again. But don’t despair: there are some tactics that can help you turn boring small talk into an energising conversation.</p> <p><strong>Put yourself out there </strong></p> <p>Improv performer Natalie Metcalfe’s job is to keep a scene going – to create an exchange that’s compelling for both the people involved and for a live audience.</p> <p>“In improv, it’s all about offers,” she says, referring to the act of bringing new information into the dialogue. Through these back-and-forths, the relationship between the characters is established and that kicks things off. “It’s the same thing in a regular conversation. You’re constantly making offers to see if you and the person you’re talking to can connect.”</p> <p>An offer in real life can be as simple as complimenting someone on what they’re wearing, and asking them about it. You can try sharing something you recently learned, or an interest you’ve just developed, creating an opening for the other person to ask you a question. Or, you can describe a relatable problem you’re having – a noisy neighbour, a plant that’s not thriving, a question of etiquette – as a prompt for advice, or some cooperative troubleshooting.</p> <p>One of Todd’s go-to approaches is to share a personal story of her own that relates to the other person’s experience. “If I find out someone has been to a place I’ve travelled, I’ll tell them an anecdote about what I did there, and ask them to share their own story.”</p> <p>Of course, putting yourself out there can sometimes feel scary, even when you’re not on stage. But Misha Glouberman, who runs a course called How to Talk to People About Things, says taking that leap pays off.  “A lot of the time in conversations, there’s something we’re interested in, but there’s a part of us that doesn’t want to take the risk of revealing it because we think it might be boring or inappropriate.” But the result of following those internal cues of fascination has the opposite effect, he says. “People like learning about other people’s interests. So be more open about yours, and a little more curious about theirs as well.”</p> <p><strong>Be inquisitive and listen </strong></p> <p>Radio interviewer Terry Gross once said, that the only icebreaker you’ll ever need is, “Tell me about yourself.” Instead of asking a pointed question like “What do you do?”, this type of open question gives someone a chance to offer up a topic they might be more excited to discuss.</p> <p>“Talking about yourself is really pleasurable. It activates the exact same hormone in your brain as sex,” says Celeste Headlee, the author of We Need to Talk: How to Have Conversations That Matter. “Another tip you can take from neuroscience is that if you start a conversation by allowing someone to feel good about themselves, then they’ll be more open to new ideas and new thoughts for the rest of the conversation.”</p> <p>Of course, upping your curiosity quotient needs to be paired with actually paying attention to the answer. “Listening is hard for homo sapiens. It’s not something our species does easily,” says Headlee.</p> <p>Indeed, people often start crafting their response before the person they’re talking to has finished speaking. Or they’ll get distracted, thinking about an email they forgot to answer. Since a great conversation is by definition a two-way street, these habits have the effect of ending one before it can even begin. Intentional listening, on the other hand, is a key to an empathetic, engaging dialogue.</p> <p><strong>Use disagreement wisely </strong></p> <p>According to Headlee, one of the other things that gets in the way of a meaningful conversation is the all-too-human need to be right. “A really common mistake is the ‘well, actually’ response,” she says, referring to that deflating moment when a person lets their need to correct you about a small detail you’ve just mentioned get in the way of continuing a story. “Google has made this worse,” she adds. “You’ll say, I went to the hotel with the largest patio in the entire world, and while you’re still talking, the person is already on their phone looking to see if that’s actually true.”</p> <p>But while trivial arguments can be an obstacle to a good conversation, Glouberman points out that differences of opinion can also help propel a chat into richer territory. “We assume that the world is just as we see it, that we see it directly,” he says. “But of course all of psychology and neuroscience tells us that’s not the case.”</p> <p>A respectful disagreement, if the other party is open to it, is a great opportunity to enrich your view of the world by understanding someone else’s.</p> <p><em>Image credits: Getty Images</em></p> <p><em>This article originally appeared on <a href="https://www.readersdigest.com.au/uncategorized/try-these-tricks-the-next-time-small-talk-becomes-unbearable" target="_blank" rel="noopener">Reader's Digest</a>. </em></p>

Relationships

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5 ways to protect your voice while barracking for the Matildas – and how to treat a hoarse voice after

<p><a href="https://theconversation.com/profiles/amy-hume-1393423">Amy Hume</a>, <em><a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a></em></p> <p>“It was definitely loud,” said Matildas player Caitlin Foord last week after the team played Denmark in Sydney, <a href="https://sport.optus.com.au/news/womens-world-cup-2023/os61164/matildas-beat-denmark-wwc-caitlin-foord-wish-loud-crowd-sydney">adding "</a>I loved it. We definitely hear it, we feel it and the louder the crowd I feel the better we are."</p> <p>Now fans are set to get even louder, whether watching at home or in a stadium, as the Australian team prepare to face England in their first-ever World Cup semi final.</p> <p>While the Matildas are warming up their limbs and muscles pre-match, spectators need to warm up our vocal folds. With a barracking job to do, we need to be match-fit. Here’s why.</p> <h2>Why do we need to warm up at all?</h2> <p>A sudden night of cheering can lead to vocal strain. The short-term risk is that you have a hoarse voice for a couple of days. Repeated vocal abuse can lead to <a href="https://www.hopkinsmedicine.org/health/conditions-and-diseases/voice-disorders">permanent damage</a> that may require therapy or surgery.</p> <p>But with some good habits and preparation, you’ll be able to get loud safely. Here are five ways to build vocal stamina for tonight.</p> <h2>1. Get your body ready</h2> <p>The amount of volume you can have in your voice all begins with your body. If you are feeling tight, especially around the neck and shoulders, the muscles around the vocal folds may <a href="https://britishvoiceassociation.org.uk/voicecare_muscle-tension-dysphonia.htm">overcompensate</a>, giving you a tired or strained feeling. Before the match, take a moment to stretch your neck and shoulders for a more open and relaxed throat, ready to roar.</p> <p>And just as the Matilda’s will aim to stay well hydrated, you should too to <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925668/">protect your voice</a>. The vocal structures consist of soft tissues that vibrate better when wet.</p> <h2>2. Yawn – even though you’re excited</h2> <p>Yawning stretches your soft palate (the fleshy back portion of the roof of the mouth) and its flexibility is essential for safe screaming. A vocal technique called <a href="https://pubmed.ncbi.nlm.nih.gov/8353622/">yawn-sigh</a> can also help stretch and warm up the structures like the tongue and pharynx (the passage at the top back of the throat) that are important for voice.</p> <p>Try yawning “horizontally” – smiling widely as you yawn. Then try yawning in the usual “vertical” way. When yawning horizontally, you should feel a different stretch in the back of your mouth and throat that targets your soft palate.</p> <figure><iframe src="https://www.youtube.com/embed/aFxKt1sexVc?wmode=transparent&amp;start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe><figcaption><span class="caption">‘Yawn a lot,’ says actor Morgan Freeman. ‘It relaxes your throat muscles, it relaxes your vocal chords.’</span></figcaption></figure> <h2>3. Breathe</h2> <p>If the semi final is anything like the <a href="https://www.abc.net.au/news/2023-08-13/matildas-world-cup-win-over-france-game-stopped-nation/102723254">quarter final against France</a>, it may be hard to remember to breathe. But breath gives your voice <a href="https://voicefoundation.org/health-science/voice-disorders/anatomy-physiology-of-voice-production/breakdowns-result-voice-disorders/#:%7E:text=If%20the%20airflow%20source%20is,for%20long%20periods%20of%20time.">power</a>.</p> <p>If you roar and cheer without a decent in-breath, the muscles of your throat will tense and strain to try to make the sound louder. It’s not efficient and will tire you out quickly. So every time you go to cheer, allow a big breath in first.</p> <h2>4. Work out your vocal folds</h2> <p>Your voice is like a muscle – actually a <a href="https://www.ncbi.nlm.nih.gov/books/NBK535342/">complex arrangement</a> of cartilage, muscle, ligaments and soft layers. If you stretch it before a workout, it will not only make the exercise easier but also aid recovery time.</p> <p>Your vocal folds are small bands of muscle in the larynx, and you can think of them like elastic. If unused, they can lose stretch and have less vibration capacity to produce sound.</p> <p>Simple exercises like humming and lip trilling can help keep the elasticity of your vocal folds. Start with <a href="https://www.tandfonline.com/doi/abs/10.1179/136132802805576436?journalCode=yslh19">humming</a> at a comfortable pitch and glide up and down your range.</p> <figure><iframe src="https://www.youtube.com/embed/Ddal_OAzkLQ?wmode=transparent&amp;start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe><figcaption><span class="caption">The vocal folds in action.</span></figcaption></figure> <h2>5. Put your whole self into it</h2> <p>Your <a href="https://www.frontiersin.org/articles/10.3389/fnins.2016.00506/full">voice, body and emotions</a> are constantly taking cues from one another. If you allow your body to be expressive, your voice will follow. Let your fandom take over your whole body and come into your face too – gestures and facial expressions change the sound of your voice and can bring enormous energy to your roars.</p> <p>Fully commit and trust your body and voice. When we are completely connected to communication, huge breaths can fly in, sound travels up through the vocal folds and rings through the body, giving your voice enormous carrying power.</p> <p>If you try to make your voice low pitched when it wants to come out high, or you hold back from being loud when your voice wants to be heard, tension can come into your throat and lead to strain.</p> <h2>How to treat your voice after the match</h2> <p>You got excited. You overdid the shouting. Understandable! After a full match, you may feel some level of <a href="https://pubmed.ncbi.nlm.nih.gov/20840041/#:%7E:text=Vocal%20fatigue%20is%20defined%20by,component%20of%20other%20voice%20disorders.">vocal fatigue</a>. If your voice sounds rough, hoarse or scratchy with unpredictable pitch, you might have what speech pathologists and ear, nose and throat (ENT) specialists call <a href="https://www.ncbi.nlm.nih.gov/books/NBK565881/">dysphonia</a>.</p> <p>As the Matildas jump in an ice bath, it’s your time to give your voice some TLC.</p> <p>Stretching, yawning, deep breathing and gentle <a href="https://www.ncbi.nlm.nih.gov/books/NBK534632/">voice exercises</a> like humming and trills work for recovery as well as warming up. An exercise I use with actors after a show is gentle whimpering sounds (like a puppy) to soothe vocal folds. Although it’s not widely researched, actors love it.</p> <p>Again, <a href="https://www.nidcd.nih.gov/health/taking-care-your-voice">hydration</a> is important for vocal hygiene, so drink up or <a href="https://www.sciencedirect.com/science/article/abs/pii/S0892199716304805">try a humidifier</a>. Special techniques like <a href="https://pubmed.ncbi.nlm.nih.gov/30408272/">singing through a straw</a> into a half-glass of water can help. Avoid whispering, which can <a href="https://pubmed.ncbi.nlm.nih.gov/16503476/">produce more strain</a> than talking naturally. <a href="https://www.enthealth.org/be_ent_smart/how-to-prevent-hoarseness-dysphonia/">Avoid</a> smoking or smoky spaces, excessive throat clearing and alcohol or caffeine that can dry out the throat and thicken mucus.</p> <p>With all the love behind the Matildas, they’ve got a chance of reaching the World Cup final. Even more reason to look after your voice and maintain match fitness. Go Matildas!<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/211499/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><em><a href="https://theconversation.com/profiles/amy-hume-1393423">Amy Hume</a>, Lecturer In Theatre (Voice), Victorian College of the Arts, <a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/5-ways-to-protect-your-voice-while-barracking-for-the-matildas-and-how-to-treat-a-hoarse-voice-after-211499">original article</a>.</em></p>

Body

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Do psychedelics really work to treat depression and PTSD? Here’s what the evidence says

<p><em><a href="https://theconversation.com/profiles/sam-moreton-194043">Sam Moreton</a>, <a href="https://theconversation.com/institutions/university-of-wollongong-711">University of Wollongong</a></em></p> <p>As of July 1, authorised psychiatrists have been allowed to prescribe MDMA (the chemical found in “ecstasy”) to treat post-traumatic stress disorder (PTSD), and psilocybin (found in “magic mushrooms”) to treat depression that hasn’t responded to other treatment.</p> <p>Psychedelic therapies have researchers excited because evidence suggests they might have lasting beneficial effects on factors that cause psychological distress beyond the treatment period. These include <a href="https://link.springer.com/article/10.1007/s00213-017-4701-y">feeling disconnected from other people</a>, <a href="https://link.springer.com/article/10.1007/s00213-019-05391-0">fear of death</a>, and <a href="https://www.sciencedirect.com/science/article/pii/S2212144719301140?casa_token=OP6tKGxjPHAAAAAA:NTQ4khgsOY5wmsQ5HzCMcZ4eZ43wQV-sdhUbf5LXFiIeKWNwdonhfCxo77k7QbNk4G69EfX-">rigid ways of thinking</a>.</p> <p>This stands in contrast to most medications for psychological issues, which only directly help while people keep taking them regularly.</p> <p>But how strong is the evidence for psychedelic therapy?</p> <h2>Early promise</h2> <p>Early results from studies around the world have found psychedelic therapy <a href="https://www.ranzcp.org/getmedia/0cf57ea2-0bd7-4883-9155-d2ba1958df86/cm-therapeutic-use-of-mdma-for-ptsd-and-psilocybin-for-treatment-resistant-depression.pdf">might be effective</a> for treating a range of psychological issues.</p> <p>For instance, most studies (<a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2032994">but not all</a>) have found patients tend to report <a href="https://pubmed.ncbi.nlm.nih.gov/37357767/">fewer depression symptoms</a> for periods ranging from several weeks to several months after psilocybin therapy.</p> <p>Similarly, studies have found <a href="https://journals.sagepub.com/doi/10.1177/0269881120965915">reductions in PTSD symptoms</a> three weeks after MDMA therapy.</p> <h2>Not so fast</h2> <p>However, as psychedelic research has grown, <a href="https://pubmed.ncbi.nlm.nih.gov/35243919/">limitations</a> of the research have been identified by researchers both <a href="https://psyarxiv.com/ak6gx/">within</a> and <a href="https://www.sciencefictions.org/p/psychedelics">outside</a> the psychedelic field.</p> <p>One issue is that we aren’t sure whether findings might be due to a <a href="https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/placebo-effect">placebo effect</a>, which occurs when a treatment works because people expect it to work.</p> <p>In clinical trials, participants are often given either a medication or a placebo (inactive) drug – and it’s important they don’t know which they have been given. However, due to the strong effects, it is difficult to prevent participants from knowing whether they have been given a psychedelic drug.</p> <p>Researchers have tried to use a range of different drugs (such as Ritalin) as a placebo in order to “trick” those participants not given a psychedelic into thinking they have received one. But this can be difficult to achieve.</p> <p>In 2021, researchers <a href="https://www.tandfonline.com/doi/full/10.1080/17512433.2021.1933434?casa_token=Dovn7x_rkdUAAAAA%3AsPzBTYNTPnNwqj9NvwN0m9ptrP4x4-c83gp3tGcshs30dWHNnmB_Vx-X5H5Y3pZJdG02IWW6X2E">reviewed</a> clinical trials involving psychedelics such as LSD, psilocybin, and dimethyltryptamine (found in animals and plants) for mood and anxiety disorders. They found trials either had not assessed whether participants guessed correctly which drug they had been given, or that this had been tested and participants tended to guess correctly.</p> <p>More recent trials <a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2032994">either don’t measure this</a> or find participants have a <a href="https://journals.sagepub.com/doi/full/10.1177/02698811231154852?casa_token=VsPt344fVGwAAAAA%3AA-i1VPBE1EWyFITWNncZEt876lWMiC7rtTOLJBQnb2pHI2775imUJhrzeSZW6r9doaBeDaj61D0">pretty good idea</a> of whether they’ve had a placebo or a psychedelic drug.</p> <p>Given the publicity and excitement around psychedelic research in recent years, it is likely most participants have <a href="https://culanth.org/fieldsights/the-pollan-effect-psychedelic-research-between-world-and-word">strong beliefs</a> such therapies work. This could lead to a significant placebo effect for participants given a psychedelic dose. Additionally, participants who realise they have received a placebo could experience <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184717/">disappointment and frustration</a>, resulting in worse symptoms. The benefits of a psychedelic may seem even greater when they are compared to the experiences of disappointed participants.</p> <h2>Translating trials to practice</h2> <p>Anecdotally, patients might be motivated to report they have gotten better, even when they haven’t.</p> <p>On a 2021 podcast, one clinical trial participant <a href="https://www.psymposia.com/powertrip/">described</a> how, in hindsight, the information they provided to the trial did not accurately capture the worsening of their symptoms. Trial participants are likely aware their results might affect whether treatments are legalised. They may not want to “ruin” the research by admitting the treatment didn’t work for them.</p> <p>There is also uncertainty about whether the findings from clinical trials mean treatments will work in private practice. There may be a lack of clarity around <a href="https://psyarxiv.com/ak6gx/">how trial participants</a> are recruited and selected. Therefore participants may not represent the typical person with PTSD or treatment-resistant depression.</p> <p>And while <a href="https://journals.sagepub.com/doi/full/10.1177/02698811211069100">the safety of psychedelics</a> within controlled contexts is often emphasised by advocates, less is known about safety of psychedelic therapy <a href="https://www.frontiersin.org/articles/10.3389/fpsyt.2021.737738/full">outside</a> clinical trials.</p> <h2>Resolving issues</h2> <p>These issues do not mean the promising psychedelic research conducted over the past several decades is worthless. Nevertheless, a <a href="https://pubmed.ncbi.nlm.nih.gov/35285280/#full-view-affiliation-1">recent review</a> of the effects of MDMA and psilocybin on mental, behavioural or developmental disorders by Australian researchers concluded the “overall certainty of evidence was low or very low”.</p> <p>Dutch researchers recently drafted a <a href="https://psyarxiv.com/ak6gx/">roadmap for psychedelic science</a> with a checklist for future research to help avoid these pitfalls. When more research is done, it might turn out psychedelic treatments help patients and don’t come with unacceptable harms – we simply don’t know that yet.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/208857/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/sam-moreton-194043">Sa<em>m Moreton</em></a><em>, Associate Lecturer, School of Psychology, <a href="https://theconversation.com/institutions/university-of-wollongong-711">University of Wollongong</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/do-psychedelics-really-work-to-treat-depression-and-ptsd-heres-what-the-evidence-says-208857">original article</a>.</em></p>

Mind

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“The heart of Hollywood” Treat Williams dead at 71

<p dir="ltr">Richard Treat Williams, a Hollywood heavyweight with over 129 acting credits to his name, has passed away at the age of 71.</p> <p dir="ltr">The actor was involved in a tragic accident with a car while riding his motorbike in Dorset, Vermont. Treat was the only person who sustained injuries in the crash, and while a helicopter was called in to airlift him to hospital, he sadly passed away. </p> <p dir="ltr">As Dorset’s fire chief Jacob Gibble told <em>People</em>, investigators believed that the car’s driver had been turning and didn’t notice the motorbike. </p> <p dir="ltr">And Treat’s agent of 15 years, Barry McPherson, said the same while confirming the news to the publication.</p> <p dir="ltr">“He was killed this afternoon. He was making a left or a right [and] a car cut him off," McPherson said. "I'm just devastated. He was the nicest guy. He was so talented.</p> <p dir="ltr">"He was an actor's actor. Filmmakers loved him. He's been the heart of Hollywood since the late 1970s. He was really proud of his performance this year. He's been so happy with the work that I got him. He's had a balanced career."</p> <p dir="ltr">Treat’s family later issued a statement regarding his passing to Deadline, where they shared that “it is with great sadness that we report that our beloved Treat Williams has passed away tonight in Dorset, Vermont after a fatal motorcycle accident. </p> <p dir="ltr">“As you can imagine, we are shocked and greatly bereaved at this time. Treat was full of love for his family, for his life and for his craft, and was truly at the top of his game in all of it. It is all so shocking right now, but please know that Treat was dearly and deeply loved and respected by his family and everyone who knew him. </p> <p dir="ltr">“We are beyond devastated and ask that you respect our privacy as we deal with our grief. To all his fans, please know that Treat appreciated all of you and please continue to keep him in your hearts and prayers.”</p> <p dir="ltr">Treat is survived by his wife of 35 years, Pam Van Sant, and their two children, Gill and Ellie, as well as his significant Hollywood legacy. </p> <p dir="ltr">He was a star across both the screen and stage over the course of his impressive career, with over 50 years of experience behind him. From <em>Prince of the City</em> to<em> A Streetcar Named Desire</em>, <em>Hair</em>, <em>Chicago Fire</em>, <em>Everwood</em>, and <em>Miss Congeniality 2</em>, he’d dipped his toes in a wide variety of content.</p> <p dir="ltr">Treat won over fans and co-workers alike with his presence, and they felt the weight of his passing, taking to social media to share their grief, and to pay tribute to the late star. </p> <p dir="ltr">“We are heartbroken over the passing of beloved … star of <em>Chesapeake Shores</em>, <em>The Christmas House</em> and so much more,” the Hallmark Channel wrote. “We will forever cherish him in our hearts, and extend our condolences to Treat’s family, friends, and loved ones.”</p> <p dir="ltr">“Working with Treat Williams in Mamet’s <em>Speed the Plow</em> at Williamstown in ‘91 was the start of great friendship. Damn it, damn it. Treat, you were the best. Love you,” writer and director Justine Bateman shared. </p> <p dir="ltr">“Treat Williams was a passionate, adventurous, creative man. In a short period of time, he quickly befriended me &amp; his adventurous spirit was infectious. We worked on just 1 film together but occasionally connected over the years. Kind and generous with advice and support. RIP,” actor Wendell Pierce said of Treat. </p> <p dir="ltr">And on behalf of many, actor Billy Baldwin noted down just a handful of the qualities he would remember his friend by, writing that “he truly and deeply cared about what’s going on here in America and around the world. Climate change, social justice, freedom, truth, tolerance… love. Beloved by his family, friends, fans, colleagues… his community. </p> <p dir="ltr">“A terrible loss. You will be missed.”</p> <blockquote class="twitter-tweet"> <p dir="ltr" lang="en">He had it all.<br />Smart.<br />Talented.<br />Funny.<br />Charming.<br />Successful.<br />Handsome.<br />Compassionate.<br />Heart of gold.<br />And that name… Treat Williams.</p> <p>He truly and deeply cared about what’s going on here in America and around the world. Climate change, social justice, freedom, truth, tolerance…… <a href="https://t.co/7cKP4nETTz">pic.twitter.com/7cKP4nETTz</a></p> <p>— Billy Baldwin (@BillyBaldwin) <a href="https://twitter.com/BillyBaldwin/status/1668458525335646208?ref_src=twsrc%5Etfw">June 13, 2023</a></p></blockquote> <p dir="ltr"><em>Images: Getty</em></p>

News

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Why understanding how spiders spin silk may hold clues for treating Alzheimer’s disease

<p><a href="https://theconversation.com/profiles/michael-landreh-1328287">Michael Landreh</a>, <em><a href="https://theconversation.com/institutions/karolinska-institutet-1250">Karolinska Institutet</a></em> and <a href="https://theconversation.com/profiles/anna-rising-1440132">Anna Rising</a>, <em><a href="https://theconversation.com/institutions/karolinska-institutet-1250">Karolinska Institutet</a></em></p> <p>Really, we should envy spiders. Imagine being able to make silk like they do, flinging it around to get from place to place, always having a <a href="https://pubs.acs.org/doi/10.1021/acsmacrolett.8b00678">strong-as-steel safety line</a> or spinning a comfy hammock whenever they need a rest.</p> <p>The fascinating properties of spider silk make it no wonder that scientists have been trying to unravel its secrets for decades.</p> <p>If we could understand and recreate the spinning process, we could produce artificial spider silk for a <a href="https://www.sciencedirect.com/science/article/abs/pii/S0141813021021292">range of medical applications</a>. For example, artificial silk can help <a href="https://doi.org/10.1016/j.biomaterials.2021.120692">regenerate the nerves that connect our brain and limbs</a>, and can shuttle <a href="https://doi.org/10.1021/acs.biomac.0c01138">drug molecules directly into the cells where they are needed</a>.</p> <figure><iframe src="https://www.youtube.com/embed/zNtSAQHNONo?wmode=transparent&amp;start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe></figure> <p>Spider silk is made of <a href="https://www.sciencedirect.com/topics/engineering/spidroins">proteins called spidroins</a>, which the spider stores in a silk gland in its abdomen. There are several types of spidroin for spinning different sorts of silk. Spiders <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673682/">store them as a liquid</a> that resembles oil droplets.</p> <p>But one of the questions that has eluded scientists so far is how spiders turn these liquid droplets into silk. We decided to investigate why the spidroins form droplets, to get us closer to replicating a spider’s spinning process.</p> <h2>Weaving a web</h2> <p>The trick that spiders use to speed up their spinning process can be used to spin better artificial silk, or even develop new spinning processes.</p> <p>In 2017, we learned to <a href="https://www.nature.com/articles/ncomms15504">make synthetic silk fibres</a> by emulating the silk gland, but we did not know how things work inside the spider. Now we know that forming droplets first <a href="https://pubmed.ncbi.nlm.nih.gov/37084706/">speeds up the conversion to these fibres</a>.</p> <p>An important clue to how the droplets and fibres are related came from an unexpected area of our research – on <a href="https://pubmed.ncbi.nlm.nih.gov/23013511/">Alzheimer’s and Parkinson’s diseases</a>. Proteins that are involved in these diseases, called <a href="https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/alpha-synuclein#:%7E:text=%CE%B1%2DSynuclein%20is%20a%20highly,linked%20to%20familial%20Parkinson%20disease.">alpha-synuclein</a> and <a href="https://www.alz.org/media/Documents/alzheimers-dementia-tau-ts.pdf">tau</a>, can assemble into tiny, oil-like droplets in human cells.</p> <p>Tau is a protein that helps stabilise the internal skeleton of nerve cells (neurons) in the brain. This internal skeleton has a tube-like shape through which nutrients and other essential substances travel to reach different parts of the neuron.</p> <p>In Alzheimer’s disease, an abnormal form of tau builds up and clings to the normal tau proteins, creating “tau tangles”.</p> <p>Alpha-synuclein is found in large quantities in <a href="https://www.webmd.com/mental-health/what-is-dopamine">dopamine-producing nerve cells</a>. Abnormal forms of this protein are linked to Parkinson’s disease.</p> <figure class="align-center zoomable"><a href="https://images.theconversation.com/files/528217/original/file-20230525-25-p40y48.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=1000&amp;fit=clip"><img src="https://images.theconversation.com/files/528217/original/file-20230525-25-p40y48.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/528217/original/file-20230525-25-p40y48.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=600&amp;h=400&amp;fit=crop&amp;dpr=1 600w, https://images.theconversation.com/files/528217/original/file-20230525-25-p40y48.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=600&amp;h=400&amp;fit=crop&amp;dpr=2 1200w, https://images.theconversation.com/files/528217/original/file-20230525-25-p40y48.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=600&amp;h=400&amp;fit=crop&amp;dpr=3 1800w, https://images.theconversation.com/files/528217/original/file-20230525-25-p40y48.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;h=503&amp;fit=crop&amp;dpr=1 754w, https://images.theconversation.com/files/528217/original/file-20230525-25-p40y48.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=754&amp;h=503&amp;fit=crop&amp;dpr=2 1508w, https://images.theconversation.com/files/528217/original/file-20230525-25-p40y48.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=754&amp;h=503&amp;fit=crop&amp;dpr=3 2262w" alt="Beautiful spider web with water drops close-up" /></a><figcaption><span class="caption">The trick spiders use to speed up their spinning process can be used to spin better artificial silk.</span> <span class="attribution"><a class="source" href="https://www.shutterstock.com/image-photo/beautiful-spider-web-water-drops-close-155560781">Aastels/Shutterstock</a></span></figcaption></figure> <p>Oil droplets of either one of these proteins form in humans when they become entangled, like boiled spaghetti on a plate. At first, the proteins are flexible and elastic, much like spidroin oil droplets.</p> <p>But if the proteins remain entangled, they get stuck together which alters their shape, changing them into rigid fibres. These can be toxic to human cells – for example, in neurodegenerative conditions such as Alzheimer’s.</p> <p>However, <a href="https://pubmed.ncbi.nlm.nih.gov/33148640/">spidroins can form droplets</a> too. This left us wondering if the same mechanism that causes neurodegeneration in humans could help the spider to convert liquid spidroins into rigid silk fibres.</p> <p>To find out, we used a <a href="https://www.nature.com/articles/nchembio.2269">synthetic spidroin called NT2RepCT</a>, which can be produced by bacteria. Under the microscope, we could see that this synthetic spidroin formed liquid droplets when it was dissolved in phosphate buffer, a type of salt found in the spider’s silk gland. This allowed us to replicate spider silk spinning conditions in the lab.</p> <h2>Silky science</h2> <p>Next, we studied how the spidroin proteins act when they form droplets. To answer this question, we turned to an analysis technique <a href="https://www.britannica.com/science/mass-spectrometry">called mass spectrometry</a>, to measure how the weight of the proteins changed when they formed droplets. To our surprise, we saw that the spidroin proteins, which normally form pairs, instead split into single molecules.</p> <p>We needed to do more work to find out how these protein droplets help spiders spin silk. Previous research has shown spidroins have different parts, called domains, with separate functions.</p> <p>The end part of the spidroin, called c-terminal domain, makes it form pairs. The c-terminal also starts <a href="https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001921">fibre formation when it comes into contact with acid</a>.</p> <p>So, we made a spidroin which contained only the c-terminal domain and tested its ability to form fibres.</p> <p>When we used phosphate buffer to entangle the proteins into droplets, they turned into rigid fibre instantly. When we added acid without first making droplets, fibre formation took much longer.</p> <p>This makes sense since the spidroin molecules must find each other when forming a fibre. Entangling the spidroins like spaghetti helps them rapidly assemble into silk.</p> <p>This finding tells us how the spider can instantly convert its spidroins into a solid thread. It also uncovered how nature uses the same mechanism that can make brain proteins toxic to create some of its most amazing structures.</p> <p>The surprising parallel between spider silk spinning and fibres toxic to humans could one day lead to new clues about how to fight neurodegenerative disorders.</p> <p>Scientists may use spider silk research, including what we have learned about the spider silk domains, to keep human proteins from sticking together – to stop them from becoming toxic. If spiders can learn how to keep their sticky proteins in check, perhaps so can we.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/205857/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /></p> <p><a href="https://theconversation.com/profiles/michael-landreh-1328287">Michael Landreh</a>, Researcher, Department of Microbiology, Tumor and Cell Biology, <em><a href="https://theconversation.com/institutions/karolinska-institutet-1250">Karolinska Institutet</a></em> and <a href="https://theconversation.com/profiles/anna-rising-1440132">Anna Rising</a>, Researcher in Veterinary medicine biochemistry, <em><a href="https://theconversation.com/institutions/karolinska-institutet-1250">Karolinska Institutet</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/why-understanding-how-spiders-spin-silk-may-hold-clues-for-treating-alzheimers-disease-205857">original article</a>.</em></p> <p><em>Images: Getty</em></p>

Body

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Why you need to treat money just like you do health and fitness

<p>Have you heard of Fitbits? They are devices designed to help you set personal health goals and track your progress, keeping you motivated – and they’re rapidly rising in popularity.</p> <p>Since Fitbits combine goal setting, progress tracking and the reward (of reaching your fitness goals) they’ve been lauded as successful in encouraging sustainable behavourial change and improving health.</p> <p>But it’s not the big things that have to change – baby steps help. Or in the case of fitness, literal steps – counting each of the little, regular actions you do every day and integrating that into your daily routine is achievable, thus has a better payoff.</p> <p>In similar vain, small behavioural changes that you can monitor for a longer-lasting and sustainable change to your finances is an important cornerstone to financial success.</p> <p>It may seem boring to spend less than you earn, pay off all your credit card debt every month on time, make extra mortgage repayments or salary sacrifices into your super. But in the end, it all adds up.</p> <p>Downloading budget apps for your phone or computer that can track your spending will help you both see your spending on a daily or weekly basis, and help you decide what small, repeatable actions you can do in order to save. Perhaps it’s dropping your would-be morning latte money into your savings account for the week and having one at home before you leave instead.</p> <p>Whatever it is that you choose to do in order to reach your financial goals, make sure you have a means of staying accountable. You could ask your partner, a friend, your accountant or financial planner.</p> <p>And when you reach your milestones? Celebrate! You’re making progress on getting and staying financially fit. </p> <p><em>Image credit: Shutterstock</em></p> <p><strong>Related links: </strong></p> <p><strong><em><span style="text-decoration: underline;"><a href="../finance/money/2015/09/aussie-credit-cards-pay-extra/">Australian credit card holders are paying too much</a></span></em></strong></p> <p><strong><em><span style="text-decoration: underline;"><a href="../finance/money/2015/08/asking-for-discounts/">5 things you should say to save money</a></span></em></strong></p> <p><strong><em><span style="text-decoration: underline;"><a href="../finance/money/2015/08/do-you-need-funeral-insurance/">Should you get funeral insurance?</a></span></em></strong></p>

Money & Banking

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6 essential tips and tricks for your kitchen

<p>Whether you’re friends with a professional chef, watch every cooking show on which you can lay your eyeballs, or your mum was some kind of wise, kitchen magician, it seems that everyone has their very own secret cooking tips to make life easier, or at least less stressful, in the kitchen. We’ve gathered a few of our own just in case no one’s ever shared them with you until now.</p> <p><strong>1. Where there’s smoke…</strong></p> <p>People often think that setting off the smoke detectors is a sign of an unskilled cook, but, as long as you’re not burning anything, don’t be afraid of a little smoke or vapour. Some foods just need that extra heat to reach their flavourful best, and that’s okay. Just make sure you’re safe.</p> <p><strong>2. Dressing in a jar</strong></p> <p>If you’re not a fan of off-the-shelf salad dressings, the natural solution to lifeless salads is making your own dressing. The annoying part of that is mixing such small quantities of ingredients in a bowl can be ridiculously fiddly. Next time, pop those ingredients into an old (clean) jam jar and give it a good shake. Not only will it be easier, you’re guaranteed to combine everything much better than you could with any whisk.</p> <p><strong>3. When life gives you lemons</strong></p> <p>If you’re using lemons or limes when you’re cooking, save the leftover skins once you’ve juiced them. You can use them to disinfect your chopping board without any chemicals. Plus, the smell is pretty fantastic.</p> <p><strong>4. Perfect pasta</strong></p> <p>When cooking pasta, the best tip we can offer is to remove the noodles from their water just before they’re completely cooked. Then, with just a little bit of the starchy water, pour them into the same saucepan in which you’re cooking your sauce. Cooking the pasta with the sauce for at least a minute or two will help infuse the flavours. If you’re not already cooking your pasta this way, you soon will be.</p> <p><strong>5. You crack me up</strong></p> <p>If you find that you’re constantly picking tiny shards of eggshell out of your dishes before you cook, you might want to adjust the way you crack your eggs. Rapping the eggs onto a sharp/thin edge of a bowl of counter causes these small fractures. If you crack the egg onto a flat surface, you’ll avoid a lot of the fuss. Plus, it’s really easy to do that cool one-handed egg crack this way. Bonus!</p> <p><strong>6. No-stick cheese</strong></p> <p>There’s a reason buying pre-grated cheese is so ridiculously expensive – grating cheese yourself is one of the most loathed kitchen tasks around. But if you spray your grater with a little cooking spray before you start, it will help the cheese glide over a little easier. Plus it’s going to make cleaning a dream.</p> <p><span style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;"><em>Images: Getty</em>                                                                </span></p>

Home Hints & Tips

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7 tricks to get more out of your next cruise

<p>There’s nothing quite as relaxing as a luxury cruise, and while there’s probably no way to have that bad a time on a cruise (unless you’re prone to sea sickness or afraid of deck chairs) there are ways in which you can considerably enhance your experience.</p> <p>We’ve put together a list containing seven tips and tricks for getting more out of your cruise so you truly have a cruising experience to write home about.</p> <p><strong>1. Get to your port of departure a night before</strong></p> <p>Did you know hundreds of cruisers actually miss the boat entirely because of delayed flights, traffic and bad weather? And many more get their cruise off to a bad start as a result of the fact that they’ve only managed to board by the skin of their teeth.</p> <p>Do yourself a pre-cruise favour and arrive at your port of departure a day early.</p> <p><strong>2. Don't be afraid to splurge and say Bon Voyage in style</strong></p> <p>A luxury cruise is no time to be a frugal Fred Flintstone. Get your cruise off to a great start (and look like a real hero in front of your spouse) by splashing out on champagne and roses. There's no better moment to make a toast to new adventures!</p> <p><strong>3. Avoid the pool area during busy times</strong></p> <p>This might seem strange, but when have mega cruise ships ever had enough poolside chairs to accommodate everyone? You’d be much better served by scoping around to find a place to call your own and avoiding the mass of humanity who are sitting around the pool sun-burning in tandem.</p> <p><strong>4. Eat on your own terms</strong></p> <p>Sure, it’s nice to meet and greet strangers at group dining times, but sometimes it’s also equally as nice to break up the routine. So don’t be afraid to order room service breakfast and have a picnic on your balcony or pay an extra little bit to dine at your cruise’s speciality restaurant.</p> <p><strong>5. Stay on the ship</strong></p> <p>Of course this doesn’t apply to all port calls (if you’re visiting Venice you have to see Venice) but these forced events are generally rushed, contrived and not all they’re hyped up to be. And by staying aboard the ship you have all the ships facilities (with the exception of maybe the ship throttle and steering wheel) to yourself!</p> <p><strong>6. Get a spa pass</strong></p> <p>A lot of cruises are offering these nowadays and for something as simple as $25 a day you can soak, steam and be massaged in luxury. There’s nothing like getting a luxury massage as you cruise through the pacific ocean, relieving your aches and pains.</p> <p><strong>7. Go to the disco</strong></p> <p>Even if dancing isn’t your thing, you owe it to yourself to bust a move at the ships disco. You’ll definitely meet some interesting characters there and chances are you’ll be more than willing to return to the floor the next night. It’s a vicious, funky cycle!</p> <p><em>Images: Getty</em></p>

Cruising

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Paramedic shares surprising croup candle hack

<p>For people all over, winter is the prime time for catching an unwanted cold, or feeling the brunt of a chest cough - especially in the young and old. </p> <p>But for those little ones prone to the likes of croup and other respiratory illnesses, one former paramedic and mother-of-two has shared her best bit of advice for helping those kids. </p> <p>Nikki Jurcutz, who is also CEO of the child safety organisation Tiny Hearts Education, has taken to social media to demonstrate her favourite ‘hack’ for calming a child who is having difficulty breathing. </p> <p>As Nikki explained, croup season had hit, and she had previously shared this trick a good number of times throughout her career as a paramedic.</p> <p>She went on to share that her own child is prone to croup, and that it can make sufferers “feel like they’re suffocating”, while “the more distressed and upset your child becomes, the worse the symptoms of respiratory distress become."</p> <p>“The best thing,” she explained, “[that] we can do as parents is try to keep them calm, and distract them, so we can slow their breathing down.” </p> <p>And after an audio clip of her son breathing before and after applying her unique technique - in which his breaths go from laboured to relaxed - she revealed that “if I hadn't of used this technique, we probably would have been calling an ambulance."</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/reel/Csa6V0NtTGq/?utm_source=ig_embed&amp;utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/reel/Csa6V0NtTGq/?utm_source=ig_embed&amp;utm_campaign=loading" target="_blank" rel="noopener">A post shared by Tiny Hearts (@tinyheartseducation)</a></p> </div> </blockquote> <p>Parents in her comments were grateful for the advice, with many reaching out to thank her, and others noting that they’d tried similar techniques with good results, while sharing their own for everyone else to see. </p> <p>“We do this too but with my hand pretending it’s five candles and she has to blow each one out (so I pop a finger down each time),” one wrote. “We also do it while she is using the spacer/ventolin to really encourage each inhale.”</p> <p>“Amazing, also blowing bubbles helps. I learnt yesterday when my baby needed physio,” another said. </p> <p>“Smell the roses then blow out the candles, one of my most used lines for cardiorespiratory patients,” one user shared. </p> <p>And as one other said, “Homeopathic remedy - spongia. It completely changed my child’s cough from can’t breathe to totally manageable. I would highly recommend a consult with a homeopath if you have a child who gets this recurrently because it would make such a big difference and reduce hospital visits”.</p> <p><em>Images: Instagram</em></p>

Caring

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"She treats it like a sport": Richard Wilkins reveals toughest interview

<div class="post-action-bar-component-wrapper" style="box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-size: 16px; vertical-align: baseline;"> <div class="post-actions-component" style="box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-size: 16px; vertical-align: baseline; visibility: visible;"> <div class="upper-row" style="box-sizing: border-box; margin: 8px 16px; padding: 0px; border: 0px; font-size: 16px; vertical-align: baseline; display: flex; justify-content: space-between; align-items: flex-end;"> <div class="right-box-container" style="box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-size: 16px; vertical-align: baseline; display: flex; justify-content: flex-end; color: #323338; font-family: Figtree, Roboto, Rubik, 'Noto Kufi Arabic', 'Noto Sans JP', sans-serif; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"> </div> </div> </div> </div> <div> <div> <div> <div> <div> <p dir="ltr">Richard Wilkins has opened up about the toughest interview of his career.</p> <p dir="ltr">The <em>Nine Entertainment </em>reporter revealed that a 2015 interview he did with <em>Material Girl</em> singer Madonna, kept him on his toes.</p> <p dir="ltr">"I guess Madonna would have to be up there. I've done a few interviews with her. She treats it like a sport," Wilkins revealed.</p> <p dir="ltr">In the interview, Wilkins played a drinking game with the singer, where she told him that their chat would not be "your average interview".</p> <p dir="ltr">"One of the last interviews I did with her she had a bottle of tequila and two shot glasses. She said if you ask a really good question, I'll have a shot and if you ask a really stupid question you have to have a shot."</p> <p dir="ltr">As the interview went on the two shot glasses remained empty.</p> <p dir="ltr">At one point, the singer let out an expletive in response to one of Wilkins’ questions and immediately apologised, to which Wilkins jokingly asked whether she should have a shot for swearing.</p> <p dir="ltr">"No, that's not part of the... I make up the rules to this game, OK," she quipped, with a smile creeping across her lips.</p> <p dir="ltr">The two were super competitive as the bottle of tequila remained untouched throughout the interview.</p> <p dir="ltr">When they discussed Madonna’s thirteenth album <em>Rebel Heart</em>, Wilkins finally broke the streak after asking her a question about changing her image.</p> <p dir="ltr">Without uttering a word Madonna pours him a shot, to which Wilkins groans, “Oh come on”.</p> <p dir="ltr">“I always answer the same way,” the singer justified and then told Wilkins to “drink up”.</p> <p dir="ltr">Wilkins recalled this moment as if it happened yesterday.</p> <p dir="ltr">"I said, this new record, you know you're going in a different direction... 'Oh, the reinvention question, alright here you go'," he recalled, miming pouring a drink.</p> <p dir="ltr">"It was all fun and games, but you've got to be on your toes when you interview Madonna, because she does not take any prisoners,” he added.</p> <p dir="ltr"> </p> <p dir="ltr"><em>Image: 9Honey</em></p> </div> </div> </div> </div> </div>

TV

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Shoppers left feeling nostalgic over new chocolate treats

<p dir="ltr">Chocolate lovers are in for a treat with Cadbury’s new range hitting supermarket shelves.</p> <p dir="ltr">The confectionary giant’s new “slices” range may feel quite familiar to some, especially those who often follow their sweet tooth into well-stocked bakeries, which makes perfect sense when considering the new blocks are inspired by the likes of crackle, hedgehog, and mint cream slices. </p> <p dir="ltr"><a href="https://www.cadbury.com.au/brand/cadbury-slices">The Cadbury Slices</a>, which carry a price tag of $5.50, are described by their makers as being “inspired by iconic Australian bakery slices and mixed with our iconic Cadbury chocolate to create a new way to enjoy icons, perfect for sharing.”</p> <p dir="ltr">They were an immediate hit with the masses, with one social media snack reviewer even declaring one of the new blocks to be “up there with some of my current favourites”. </p> <p dir="ltr">In a video posted to her Instagram account, she could be seen entering a Woolworths supermarket to pick up the new range, and outlined her journey before reviewing the goods. </p> <p dir="ltr">She did not, however, try the Old Gold mint cream, noting that she wasn’t really a fan of mint chocolate to begin with. </p> <p dir="ltr">First up was the Caramilk hedgehog, and after explaining the “classic Aussie no-bake slice”, she described how the block had a Caramilk base and contained almonds, toasted coconut, and rice crisps, before noting that she “absolutely loved the taste”. </p> <p dir="ltr">Next came the block “inspired by a chocolate crackle”, which also featured rice crisps and toasted coconut, and “definitely resembled the chocolate crackle flavour”. She noted that it had that “recognisable Copha taste”, although she didn’t believe that was one of the ingredients. </p> <p dir="ltr">“It was so delicious,” she surmised, “and I hope this one stays around for a while.” </p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/reel/Cr7-qyFJS1q/?utm_source=ig_embed&amp;utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/reel/Cr7-qyFJS1q/?utm_source=ig_embed&amp;utm_campaign=loading" target="_blank" rel="noopener">A post shared by Snack Reviews Aus (@snackreviews_aus)</a></p> </div> </blockquote> <p dir="ltr">Her joy at the range and their nostalgic flavours were exactly what the company had been aiming for, and as Paul Chatfield - vice president marketing for ANZ Mondelez International - told <em>news.com.au</em>, “the new Cadbury Slices range, features a variety of familiar and nostalgic flavours that Cadbury and chocolate-fans alike will enjoy.</p> <p dir="ltr">“We know Aussies share fond memories of bakery slices and hope they too will build new memories with family and friends as they share a Cadbury Slices block.”</p> <p dir="ltr"><em>Images: Instagram </em></p>

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